The Xie & Bai Research Group
Yuanyuan Xie / 谢媛媛
PhD, Professor
Vice-president of
College of Pharmaceutical Science
Tel：(0571)88320878
Email：xyycz@zjut.edu.cn
Education
Zhejiang University, Ph.D. 2003
Huaibei Normal University, B.S. 1997
Biography
Professor Xie graduated from Zhejiang University and acquired her PhD in Organic Chemistry. In 2007, she was awarded the Second Price of National Award for Science and Technology. She pursued advanced study in UK as a senior visiting scholar from 2011 to 2012. Currently she is a professor and deputy director of Collaborative Innovation Center of Green Pharmaceuticals and College of Pharmaceutical Sciences, Zhejiang University of Technology. She has published over 30 articles on leading chemistry journals including Tetrahedron, Tetrahedron Letters, Synlett, Synthesis, etc. and acquired 8 authorized invention patents.
Research Interests
Professor Xie’s research interests broadly cover the following 4 aspects:
1. Synthesis of pharmaceutical intermediates
2. Studies on the synthesis of heterocycle compounds
3. Application of hypervalent iodine reagents and ionic liquids in organic synthesis
4. Click Chemistry in the synthesis of HPO compounds
Selected Publications
1. Xiaohe Xu, Jian Sun, Yuyan Lin, Jingya Cheng, Pingping Li, Yiyan Yan, Qi Shuai*, Yuanyuan Xie*, Copper nitrate-catalyzed oxidative coupling of unactivated C(sp3)–H bonds of ethers
and alkanes with N-hydroxyphthalimide: synthesis of N-hydroxyimide esters, Organic &
Biomolecular Chemistry, 2017, 15(46): 9875-9879
2. Xiaohe Xu, Jian Sun, Yuyan Lin, Jingya Cheng, Pingping Li, Xiaoying Jiang, Renren Bai,
Yuanyuan Xie*, Iron-Nitrate-Catalyzed Oxidative Esterification of Aldehydes and Alcohols with
N-Hydroxyphthalimide: Efficient Synthesis of N-Hydroxyimide Esters, European Journal of
Organic Chemistry, 2017, 7160–7166
3. Yiyi Weng, Hao Zhou, Chen Sun, Yuanyuan Xie*, Weike Su*, Copper-Catalyzed Cyclization
for Access to 6H-Chromeno[4,3-b]quinolin-6-ones Employing DMF as the Carbon Source,
Journal of Organic Chemistry, 2017, 82 (17): 9047–9053
4. Xiaohe Xu, Pingping Li, Yingyi Huang, Chuo Tong, YiYan Yan, Yuanyuan Xie*, Atmospheric
oxidative catalyst-free cross-dehydrogenative coupling of aldehydes with N-hydroxyimides,
Tetrahedron Letters, 2017, 58(18): 1742-1746
5. Yuan-Yuan Xie#, Zidong Lu#, Xiao-Le Kong, Tao Zhou, Sukhi Bansal, Robert Hider*,
Systematic comparison of the mono-, dimethyl- and trimethyl 3-hydroxy-4(1H)-pyridones–
Attempted optimization of the orally active iron chelator, deferiprone, European Journal of
Medicinal Chemistry, 2016, 115: 132-140
6. Li Fang, Zhenhua Li*, Zhijiang Jiang, Zhiyong Tan, Yuanyuan Xie*, A Metal-Free Oxidative
Cross-Dehydrogenative Coupling of N -Aryl Tetrahydroisoquinolines and 2-Methylazaarenes
Using a Recyclable Oxoammonium Salt as Oxidant in Aqueous Media, European Journal of
Organic Chemistry, 2016, 3559–3567
7. Xiaoying Jiang, Bing Gan, Jiwei Liu, Yuanyuan Xie*, Novel Synthesis of α-Keto Esters and
Amides by an sp3 C–H Oxidation of Nitromethyl Aryl Ketones Promoted by Ion-Supported
(Diacetoxyiodo)benzene, Synlett, 2016, 27(19): 2737-2741
8. Yuanyuan Xie*, Jiwei Liu, Yingyi Huang, Lixia Yao, A novel method for synthesis of α-keto
esters with phenyliodine(III) diacetate, Tetrahedron Letters, 2015, 56(24): 3793-3795
9. Yuanyuan Xie*, Dongyan Guo, Xiaoying Jiang, Haixuan Pan, Wenhui Wang, Tingting Jin,
Zhisheng Mi, An efficient method for the synthesis of substituted 5-aminotetrazoles from
selenoureas using PhI(OAc)2, Tetrahedron Letters, 2015, 56(19): 2533-2536
10.Yuanyuan Xie*, Lehuan Li, Microwave-assisted a-halogenation of 2-methylquinolines with
tetrabutylammonium iodide and 1,2-dichloroethane (1,2-dibromoethane), Tetrahedron Letters,
2014, 55(29): 3892-3895
